Academia Sinica Logo

Example output from DNA-binding residue prediction for 1TSR Chain B for the DNA-binding protein p53

This PDB entry has 3 chains, A, B and C, with chain B in the X-Ray crystal being bound to DNA, the main DNA-binding residues are Lys120, Ser241, Arg248, Arg273, Ala276 and Arg280. All three chains have an identical structure, the prediction for chain B DNA-binding residues is made without any preknowledge of the DNA.

Welcome to DR_bind, the DNA-binding residue prediction server and the results for 1TSR chain B

Status: Job FINISHED

You can find a PyMol .pml file here for download, the original and the cleaned up PDB files and also the raw output from the prediction process. To download the files please right-click on the following links.

Original PDB file: 1TSR.orig, Original ConSurf file: 1TSR.consurf,

Cleaned PDB file: 1TSR.pdb, Pymol pml files: 1TSR.pml, Text output files: 1TSR.txt,

Predicted DR_bind DNA-binding residues in your structure

Pro177, His178, Asn239, Ser241, Cys242, Met243, Gly244, Asn247, Arg248, Arg249, Pro250, Arg273, Ala276,

The image shows the backbone of your protein structure, the predicted DR_bind DNA-binding results are depicted in red. If the image is missing, then you probably need to install a Java virtual machine from the Java website and restart your browser. Full JMol applet instructions are available.

To get information on a residue hover the mouse over that residue for ~1 second,
To rotate use left-click,
To translate use ctrl & right-click and
To zoom use the mouse wheel.
DR_bind is hosted at The Institute of Biomedical Sciences, Academia Sinica, Taipei 11529, Taiwan.